Glycyrrhizic acid extraction from liquorice

With ammoniacal alcohol extraction,glycyrrhizic acid is extracted from liquorice by powering,filtering and extracting.Some factors influencing the extraction such as temperature,time,ammonia content and ethanol contents are evaluated using the fractional factorial design.The optimum conditions for glycyrrhizic acid extraction are: temperature 40.28 ℃,time 5.84 h,ammonia content 0.41%,ethanol content 16.78%,the resulting glycyrrhizinate yield is up to 66.40%.