A comparison of the natriuretic and kaliuretic effects of cicletanine and hydrochlorothiazide in prehypertensive and hypertensive humans

Frank Wagner,Marie-Pierre Malice,Erol Wiegert,Helen E. McGrath,John J. Gildea,Shabri Mitta,Kristien Van Dyck,Inge De Lepeleire,Amy O. Johnson-Levonas,Christine McCrary Sisk,Rose Fernandez,Danielle M. Greenwalt,Chan Beals,Robert M. Carey,Irene Nunes

A comparison of the natriuretic and kaliuretic effects of cicletanine and hydrochlorothiazide in prehypertensive and hypertensive humans

2012

Frank Wagner
Marie-Pierre Malice
Erol Wiegert
Helen E. McGrath
John J. Gildea
Shabri Mitta
Kristien Van Dyck
Inge De Lepeleire
Amy O. Johnson-Levonas
Christine McCrary Sisk
Rose Fernandez
Danielle M. Greenwalt
Chan Beals
Robert M. Carey
Irene Nunes

Objectives:The aim of this study was to compare the single-dose effects of thiazide-type diuretics cicletanine and hydrochlorothiazide (HCTZ), on natriuresis and kaliuresis in prehypertensive and treatment-naive, stage 1 hypertensive patients and to explore the impact of GRK4 gene polymorphisms on t

Keywords:

Prehypertension
Endocrinology
Cicletanine
Kaliuresis
Natriuresis
Medicine
Diabetes mellitus
Hydrochlorothiazide
Internal medicine

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