Application steroid compounds substituted at position 11 for lafabricacion drug dissociated oestrogenic activity.

The invention relates to the application of steroid compounds of formula (I): wherein n, R 1, R 2 X AND Y are as defined in the description, manufacture of medicaments for the hormone replacement therapy MENOPAUSE OR perimenopause; LACK OF ACTIVITY PRESENTED IN THE TERRITORY estrogenic uterine cancer.