G291(P) Outcome of preterm infants discharged on home oxygen- retrospective study

Aim We studied the short- and long-term outcome of babies in three-way comparison between babies ( Methods Units’ practice: ‘Oximetery pass’ is defined as Infants having oxygen saturation levels >94% at least 90% of the times in Unit1 and having oxygen saturation >90% for at least 95% of the time in Unit2. We defined ‘developmental issue’ as infants with score of Results We had a total of 59 babies from each unit who were discharged on home oxygen and 104 babies discharged without home oxygen, from 2012 to 2017. There is no difference between the two units in any respiratory outcome. Number of readmissions due to respiratory illness and duration of hospital stay during readmission is not different between three groups. In the post-Hoc analysis, there is no difference in any of the respiratory, clinical outcomes and Bayley scores in babies discharged on home oxygen from both the units. Babies from Unit-2 continued to be on home oxygen for a longer period than babies discharged from Unit-1 (Mean diff: 11.9 ± S.E 3.7 weeks; p Following factors had significant correlation Home oxygen unit-1, Home oxygen unit-2, No home oxygen group, Birth weight, Gestation, Ventilation days and other variables. To test the hypothesis that Bayley score in all three domains and developmental issues is a function of above-mentioned variables, a stepwise multiple regression analysis was performed. Only ventilation days were significantly associated with BSID in all three domains (Adj R2 of 0.25, p Conclusion Discharging babies on home oxygen and discharging on home higher oxygen saturation target did not offer any benefits in short- and long-term outcomes. Duration of ventilation and ROP requiring treatment is negatively associated with BSID scores and developmental outcome.