EFFECT OF CORONARY ARTERY BYPASS ON QT DISPERSION
2006
: Introduction: QT dispersion (QT Max – QT min) reflects inhomogeneous
ventricular depolarization that may provide a substrate for serious arrythmias and
is associated with adverse clinical outcomes in patients with coronary artery
disease. Some studies have shown reduction in QT dispersion after successful
angioplasty due to coronary reperfusion, but effect of coronary artery bypass
grafting on QTd is less known. This study evaluated the effects of coronary
artery bypass grafting (CABG) on QT dispersion in first days after surgery.
Methods: In this descriptive cross-sectional study, QTd of 50 patients who
underwent coronary artery bypass grafting were calculated pre-and post-surgery
This measurement was performed after surgery on three occasions (first day,
third day and predischarge) in patients without serious or malignant arrythmias.
Results: QTd & QTcd (mean SD) decreased in third postoperative day compared
to preoperation values. QTd and QTcd decreased from 62.9 (26.9), and 64.8
(28.08) to 43.1 (22.8) and 59.4 (29.9) respectively (P
the third day after surgery comparing to presurgery. The decrements was more
significant between predischarge and preoperation: QTd decreased from
62.2(26.9) to 41.6(24.16) and QTcd decreased from 71.7(32.47) to 51.5(27.69)
(P
Conclusion: CABG, the most comprehensive method of revascularization in
patients with coronary artery disease, is an important factor in reducing QT
dispersion and eventually reducing malignat ventricular arrhythmia after surgery.
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