Application of Genomewide Association Studies in Complex Human Disease

In the past few years,people have been researching many kinds of complex human diseases and traits with genomewide association studies(GWAS),such as diabetes,tumor,cardiovascular disease,neuropsychiatric disorder,autoimmune disease,and so on,and have identified a large number of closely related genetic variation,providing important clues for further exploring the genetic characteristics of complex human disease.However,due to many factors affect complex disease,many have found genetic variations have little contribution to disease,and the mechanism is unclear,GWAS remains many problems.In this paper,we present an overview of GWAS in complex disease,and the prospect is discussed.