Extent of Arterial Tumor Enhancement Measured With Preoperative MDCT Gastrography Is a Prognostic Factor in Advanced Gastric Cancer After Curative Resection

OBJECTIVE. The objective of this study was to investigate the correlation between pathologic findings and arterial tumor enhancement at MDCT gastrography of patients with a prognosis of advanced gastric cancer after curative resection. MATERIALS AND METHODS. The cases of 41 patients with advanced gastric cancer (23 men, 18 women; age range, 35–92 years; median, 60 years) who underwent MDCT gastrography and optical endoscopy before surgery were retrospectively evaluated. Two radiologists reviewed virtual endoscopic and multiplanar reconstruction images to measure arterial phase CT values of the inner tumor margin and healthy gastric wall. They used consensus regions of interest on a cross-sectional image of the largest tumor diameter and then calculated tumor–to–normal wall enhancement ratio (TNR). Advanced gastric cancers were divided into high- and low-TNR groups with mean TNR as the cutoff. The correlations between groups and pathologic factors, patient survival, and mode of recurrence were studied. RES...