Quinazoline compound, and its application as immunosuppressant

2014 
The invention relates to a quinazoline compound. The structure of the compound is represented by a general formula shown in the specification. In the general formula, R is one of hydrogen, alkyl groups, alkenyl groups, alkynyl groups, aralkyl groups, formyl groups, halogens, nitro groups, amino groups, amido groups, acylamino groups, sulfonamide groups, hydroxy groups and alkoxy groups. The compound is a 4-{N-butyl-N-[(2'-1H-tetratriazol-5-yl)biphenyl)methyl]amine}quinazoline compound, and belongs to the field of medical immunology. The invention also relates to an application of the compound in the preparation of drugs for inhibiting Jurkat cell proliferation. The compound can well inhibit the Jurkat cell proliferation, and the drugs for inhibiting Jurkat cell proliferation prepared by using the compound can be used for autoimmune diseases and transplant rejection.
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