Children with Pertussis and Unvaccinated (Unprimed) Young Antigens in Vaccinated (Primed) pertussis Bordetella Antibody Response Patterns to

In a previous study, it was found that the antibody response to a nonvaccine pertussis antigen in childrenwho were vaccine failures was reduced compared with the response in nonvaccinated children who hadpertussis. In two acellular pertussis vaccine efficacy trials in Sweden, we studied the convalescent-phaseenzyme-linked immunosorbent assay (ELISA) geometric mean values (GMVs) in response to pertussis toxin(PT), filamentous hemagglutinin (FHA), pertactin (PRN), and fimbriae (FIM 2/3) in vaccine failures andcontrols with pertussis. In Germany, the antibody responses to