Controversies in Open Globe Injury Management

Every year, open globe injuries (OGIs) affect approximately 266,000 patients worldwide (Negrel and Thylefors B. Ophthalmic Epidemiol. 1998;5:143–69). The management of these patients remains controversial, particularly for the following areas: antibiotic prophylaxis for endophthalmitis, repair of posterior ruptures, injuries with lens disruption, repair of eyes with no light perception (NLP), and the risk for developing sympathetic ophthalmia. This chapter will review these controversial topics in the management of open globe injuries. We will first present an evidence based review of the current literature in this area, followed by an expert opinion by one of our editors.