Critical closing pressure monitoring using diffuse correlation spectroscopy in cardiac ablation patients

Monitoring critical closing pressure (CrCP) can be a useful and noninvasive measure of intracranial pressure (ICP), especially in patients with high risk factors for brain injury. We monitored five patients undergoing cardiac ablation procedures using diffuse correlation spectroscopy (DCS). We utilized the prolonged diastolic events that occur during this procedure to validate non-invasive measurements of CrCP with DCS. to estimate the gold standard CrCP during long diastolic events induced during the procedure and compared them to estimations from normal pressure and flow waveforms prior to each event.