Induction of a cytotoxin from murine macrophages by an animal lectin.

: Vertebrate lectin purified from loach eggs stimulated release of cytotoxin from BCG-or glucan (TAK)-elicited peritoneal macrophages and a murine macrophage cell line (J774.1), but not from resident peritoneal cells. The cytotoxin released from J774.1 cells on stimulation with loach egg lectin was a heat-labile protein with a molecular weight of about 55K.