Radiation and chemoradiation therapy of malignant laryngopharyngeal tumors

: The paper is concerned with the results of open field gamma-beam therapy using grid filters. A group of patients with Stage III-IV tumors received chemoradiotherapy. A single focal radiotherapeutic dose varied from 1.6 to 2.5 Gy, a summary dose from 55 to 70 Gy depending on tumor stage and histological structure. A chemotherapeutic drug was prescribed within the limits of 1/2-2/3 of a standard dose. Intensive substitution and blood-stimulating therapy was provided. With the use of different radiotherapeutic and chemoradiotherapeutic methods the 3- and 5-year survival rates were 19.8% and 14.3%, respectively.