The method for manufacturing 4- propargylation amino benzoxazinone class
2014
The present invention relates to a kind of 4- propargylation amino benzos of manufacture formula (I) The method of zionoes, including the following steps: step a) prepares propargyl chloride and reacting propargyl alcohol optionally in the presence of a catalyst with thionyl chloride;And step b) makes the propargyl chloride prepared in step (a) and the NH- benzo of formula (II) Piperazine reactive ketone;Wherein each variable is defined according to specification.
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