Advocating for Rectal Microbicides and Safe Lubricants

Anal intercourse is a common human behavior practiced by men, women, and transgender individuals across the world. Unprotected, anal intercourse is 10–20 times more likely to result in HIV infection compared with unprotected vaginal intercourse. Because male and female condoms are not universally used consistently and correctly, there is a need for new prevention technologies such as rectal microbicides (RMs). Even as RMs are being researched and developed, there is inadequate access to safe, condom-compatible lubricant for people around the world, especially in Africa. Not only is there very poor access to appropriate lubricant, science has uncovered some concerning data about the safety of sexual lubricants. A coordinated research agenda to answer the questions we have about lube safety does not yet exist, but is critical. IRMA—International Rectal Microbicide Advocates—is a global network of more than 1,200 advocates, scientists, policy makers, and funders that has prioritized advocacy efforts around these issues. Improved access to safe, condom-compatible lubricants is possible. Safe, effective, accessible, and acceptable RMs are possible. The way forward requires ongoing, substantive, meaningful, and creative engagement between and among communities, advocates, scientists, policy makers, and funders.