Prognostic Factors of Induction of Labor with Misoprostol at CHUD/B in Parakou, Benin in 2016

Introduction: Misoprostol is a molecule used for inducing labor these days in order to reduce perinatal morbidity and mortality. This study aimed at appreciating maternal and fetal prognosis after induction of labor on indication for delivery with misoprostol on live fetus at CHUD/B in 2016. Patients and Method: It was an observational case-control type study with prospective data collection carried out in the gynecology and obstetrics department of CHUD/B. Were included, 37 WA healthy pregnant women whose Bishop score was less than 6. Their fetal heart rate and their pelvis were normal. Fisher chi-2 test was used and the significance threshold of different associations was 5%. Results: In the study, 99 women involved were divided into 33 cases and 66 case-controls. The average age of cases was 29.70 ± 5.03 years old with extremes of 20 and 40 years and that of case-controls was 29.44 ± 4.96 years with extremes of 21 and 40 years. Out of the 1195 deliveries which took place in the gynecology and obstetrics department of CHUD/B, 33 inductions of labor on full-term live fetuses with misoprostol were performed that is to say a frequency of 2.76%. The factors associated with maternal and fetal prognosis were profession, mode of admission, Bishop score with respectively p-values of 0.049, 0.00005, 0.00001. Conclusion: The use of misoprostol seems beneficial as regards maternal and fetal prognoses in our practice at a low cost.