Hairy Cell Leukemia: a Clinical Review Based on 725 Cases of the Italian Cooperative Group (ICGHCL)

The Italian Registry for hairy cell leukemia (HCL) has recorded 725 patients with HCL diagnosed over 25 years. We analysed this large series of patients with the aim of providing an evaluation of changes in clinical presentation, impact of initial therapy and modifications in prognostic factors over the period of two decades.