Induction of ROS and DNA damage-dependent senescence by icaritin contributes to its antitumor activity in hepatocellular carcinoma cells

Shikang Wang,Qian Wang,Huijun Wang,Chengkun Qin,Xianping Cui,Lei Li,Yongqing Liu,Hong Chang

Induction of ROS and DNA damage-dependent senescence by icaritin contributes to its antitumor activity in hepatocellular carcinoma cells

2019

Shikang Wang
Qian Wang
Huijun Wang
Chengkun Qin
Xianping Cui
Lei Li
Yongqing Liu
Hong Chang

Context: Icaritin (ICT), a prenylflavonoid derivative extracted from the Epimedium (Berberidaceae) genus, has been identified to exhibit antitumor effect in hepatocellular carcinoma (HCC) c...

Keywords:

Berberidaceae
DNA damage
Cellular senescence
Prenylflavonoid
Hepatocellular carcinoma
Biochemistry
Biology
Epimedium
Senescence
Cancer research
antitumor activity

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