Evaluation of Canine Serum Thyrotropin (TSH) Concentration: Comparison of Three Analytical Procedures

A comparative study of 3 analytical methods (immunoradiometric assay, enzyme immunometric assay, and chemiluminescent immunometric assay) for canine serum thyrotropin (TSH) was performed. Ninety-six dogs were included in the study. The within- and between-run precision was evaluated for each method, and correlations for the results obtained with each method were examined. The best within- and between-run precision was obtained with the chemiluminescent immunometric assay. Satisfactory correlations for the 3 analytical procedures were obtained but varied in relation to serum TSH concentration.