Left Bundle Branch Block: Current and Future Perspectives.

Left bundle branch block (LBBB) may be due to conduction system degeneration or a reflection of myocardial pathology. LBBB may also develop following aortic valve disease or cardiac procedures. Patients with heart failure with reduced ejection fraction (HFrEF) and LBBB may respond positively to cardiac resynchronization therapy (CRT). Lead placement via the coronary sinus is the mainstay approach of CRT. However, other options including physiologic pacing are being explored. In this review, we summarize the salient pathophysiologic and clinical aspects of LBBB, as well as current and future strategies for management.