Synthesis of selenium linked steroidal glycoconjugates

Steroidal glycosides derivatives are found in several natural products and shows cardiotonic and anticancer activity, such as diosgine and digitoxin. On the other hand, selenoglycosides have been explored as potential anti-HIV, anticancer and antioxidants. We have recently described the synthesis of selenium linked carbohydrate and amino acid glycoconjugates. In this work we synthesized cholesterol Se-glycoconjugates by selective ring opening of cholesterol epoxide.