Time-dependent kinetic models for glutamic acid fermentation

A group of time-dependent kinetic models for glutamic acid fermentation are presented. These can divide cell growth into three stages: the positive acceleration stage, negative acceleration stage, and equilibrium stage. The substrate consumption is also divided into three stages: the negative acceleration state, positive acceleration stage, and exhaustion stage. Product formation is also separated into three stages: the lag stage, positive acceleration stage, and negative acceleration stage. By comparing data from the laboratory and factory, good agreement between experimental values and predicted values is found and in comparisons to reported models in the documents about glutamic acid fermentation, the present models are most satisfactory.