CD4+CD73+ T cells are associated with lower T-cell activation and C reactive protein levels and are depleted in HIV-1 infection regardless of viral suppression

Patrick J. Schuler,Bernard J.C. Macatangay,Zenichiro Saze,Edwin K. Jackson,Sharon A. Riddler,William Buchanan,Benedict B. Hilldorfer,John W. Mellors,Theresa L. Whiteside,Charles R. Rinaldo

CD4+CD73+ T cells are associated with lower T-cell activation and C reactive protein levels and are depleted in HIV-1 infection regardless of viral suppression

2013

Patrick J. Schuler
Bernard J.C. Macatangay
Zenichiro Saze
Edwin K. Jackson
Sharon A. Riddler
William Buchanan
Benedict B. Hilldorfer
John W. Mellors
Theresa L. Whiteside
Charles R. Rinaldo

Background The role of the adenosine (ADO) suppression pathway, specifically CD39-expressing and CD73-expressing CD4+ T cells in HIV-1 infection is unclear.

Keywords:

Immunology
Apyrase
Virology
5'-nucleotidase
ANTIGENS CD
C-reactive protein
T cell
Adenosine
Biology
Molecular biology
Flow cytometry
FOXP3
IL-2 receptor
Cyclic adenosine monophosphate

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