Metode de laborator pentru caracterizarea fizico-chimică a alergenelor recombinate ca standarde de referinţă

The methods used to quantify the physico-chemical parameters of molecular allergens are multiple. The physico-chemical parameters selected for the evaluation of the quality of natural purified and recombinant allergens include the identity of the primary structure, the secondary structure, the purity and homogeneity. However, there is no single method that can analyze all the important characteristics represented by structural, physico-chemical and immunological properties.