PRESENCE OF DEL261G (O1) AND 803C (B) ON ONE HYBRID ALLELE - A POTENTIAL CAUSE FOR MISINTERPRETATION OF PCR-SSP RESULTS

In blood group determination, discrepancies between phenoand genotypes are generally an indicator for the presence of unexpected or unknown, and usually very rare blood group alleles. In the course of routine screening RhD negative donors for the presence of RHD genes, a crosslink-ID-control PCR, specific for the B-allele of the ABO gene, tested positive in one case, although this donor had a record of blood group A at three independent blood donations.