Simple weight-based contrast dosing for standardization of portal phase CT liver enhancement

Aim To investigate the use of a weight-based volume of contrast media to optimize portal enhancement in patients undergoing abdominal computed tomography (CT). Materials and methods Thirty-one patients were assessed to establish whether a relationship existed between their weight and the portal liver enhancement achieved. Three methods of estimating weight were evaluated to establish which was the most appropriate to use in clinical practice. One hundred patients were then examined using 100 ml contrast media and 100 further patients using a weight-based contrast volume as dictated by a look-up table. The enhancement achieved by each technique was assessed. Results A good correlation was shown between patient weight and contrast enhancement when a fixed volume of contrast media was used ( r  = –0.825, p Conclusion The use of a simple, practical, weight-based look-up table to decide contrast media volumes during portal phase liver CT can greatly reduce inter-patient variability compared to a fixed-volume technique.