Superoxide dismutase and and its isoenzymes in children with juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA) is not a rare disease in children. The etiology of the disease is unknown and various parameters are useful in establishing diagnosis. The research concerning reactive oxygen species in recent years shows that chronic oxidative stress may lead to chronic inflammation. Among the antioxidant systems present in cells superoxide dismutase is one of the preventive antioxidants i.e. enzymes reducing the number of generated free radicals.