A stereocontrolled synthetic route to anti-β-amino alcohols

Abstract A physiologically indispensable β-amino hydroxy functionality has been constructed with complete anti -stereoselectivity by intramolecular iodoamidation of ( Z )-olefinic homoallylic trichloroacetimidates 4 – 6 , 18 , 20 , 30 and 32 , which comprise bulky substituents at the vinylic positions.