Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies

Ilona Hromadnikova,Bela Houbova,Dana Hridelova,Sona Voslarova,Pavel Calda,Katerina Nekolarova,Josef Kofer,David Stejskal,Jindrich Doucha,Ondrej Cinek,Jan Vavrirec

Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies

2002

Ilona Hromadnikova
Bela Houbova
Dana Hridelova
Sona Voslarova
Pavel Calda
Katerina Nekolarova
Josef Kofer
David Stejskal
Jindrich Doucha
Ondrej Cinek
Jan Vavrirec

Background We investigated fetal and total DNA levels in maternal plasma in patients bearing fetuses affected with Down syndrome in comparison to controls carrying fetuses with normal karyotype.

Keywords:

Obstetrics
Gestational age
Fetus
Down syndrome
Medicine
Karyotype
Testis determining factor
Andrology
Gynecology
Real-time polymerase chain reaction
Amniocentesis
Gestation

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