Nimodipine solid dispersant and tablet and their preparation methods

The invention discloses a nimodipine solid dispersant and tablet and their preparation methods. The preparation method of the nimodipine solid dispersant comprises the following steps of blending nimodipine, polyvinylpyrrolidone and a volatile organic solvent to obtain a uniform mixed solution, uniformly spraying the mixed solution to a filler by a fluidized bed under the conditions of atomization pressure of 1.2-3.0bar, a liquid spraying rate of 3-12g/min, an inlet air temperature of 20-80 DEG C and an inlet air amount of 20-80m /h, and carrying out granulation and drying, wherein a mass ratio of nimodipine to polyvinylpyrrolidone is 1: (1-6) and a mass ratio of nimodipine to the filler is 1: (2-15). The preparation method of the nimodipine solid tablet comprises carrying out raw material drying, adding accessory materials into the dried raw materials and carrying out tabletting. The preparation methods have simple processes. Preparation processes of the solid dispersant and tablet can be carried out simultaneously. The nimodipine solid dispersant particles have uniform particle size distribution, high solubility, good stability and high bioavailability.