Ivosidenib in Isocitrate Dehydrogenase 1-Mutated Advanced Glioma.

Ingo K. Mellinghoff,Benjamin M. Ellingson,Mehdi Touat,Elizabeth A. Maher,Macarena I. de la Fuente,Matthias Holdhoff,Gregory M. Cote,Howard A. Burris,Filip Janku,Robert J. Young,Raymond Y. Huang,Liewen Jiang,Sung Choe,Bin Fan,Katharine E. Yen,Min Lu,Chris Bowden,Lori Steelman,Shuchi Sumant Pandya,Timothy F. Cloughesy,Patrick Y. Wen

Ivosidenib in Isocitrate Dehydrogenase 1-Mutated Advanced Glioma.

2020

PURPOSEDiffuse gliomas are malignant brain tumors that include lower-grade gliomas (LGGs) and glioblastomas. Transformation of low-grade glioma into a higher tumor grade is typically associated wit...

Keywords:

Cancer research
Isocitrate dehydrogenase
Medicine
tumor grade
Glioma
Pathology

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