The highly stereospecific enzyme catalysed transamination of 4-fluorophenylglyoxylic acid to 4-(S)-fluorophenylglycine

Mark Cameron,D Cohen,Ian F. Cottrell,D.J Kennedy,Christopher Roberge,Michel Chartrain

The highly stereospecific enzyme catalysed transamination of 4-fluorophenylglyoxylic acid to 4-(S)-fluorophenylglycine

2001

Mark Cameron
D Cohen
Ian F. Cottrell
D.J Kennedy
Christopher Roberge
Michel Chartrain

Cell free extracts from a number of bacterial strains belonging to the Pseudomonas and Bacillus genera were found to catalyse the conversion of 4-fluorophenylglyoxylic acid to 4-(S)-fluorophenylglycine in high optical purity (99% ee).

Keywords:

Enzyme
Organic chemistry
Biochemistry
Chemistry
Stereospecificity
Cell
Transaminase
Pseudomonas
Enantiomeric excess
Enzyme catalysis
Transamination
Stereochemistry
cell free extracts

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations