Efficacy of Zhenjingdingzhi decoction in treating insomnia with Qi-deficiency of heart and gallbladder: a randomized, double-blind, controlled trial.
2015
Abstract Objective To evaluate the clinical efficacy of Zhenjingdingzhi decoction in treating insomnia with Qi -deficiency of heart and gallbladder. Methods We conducted a double-blind, randomized, controlled trial involving 100 patients with insomnia of Qi -deficiency of heart and gallbladder. Patients were randomly divided into the treatment group ( n = 50) and the control group ( n = 50) according to a random number table. The treatment group was given Zhenjingdingzhi decoction, while the control group was treated with Suanzaoren decoction. the pharmacological treatment lasted for 8 weeks. The clinical efficacy was assessed by using Spiegel scale, Pittsburgh sleep quality index (PSQI) and Traditional Chinese Medicine (TCM) syndrome scores. Results Comparing Spiegel scores between the two groups at 4 and 8 weeks, the differences in curative effect between the two groups were both significant (both P P P P Conclusion Zhenjingdingzhi decoction is effective and safe for the treatment of insomnia with Qi -deficiency of heart and gallbladder, especially for improving sleep quality and sleep duration.
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