5β-hydroxygoniothalamin, a Styrylpyrone Derivative from Goniothalamus dolichocarpus (Annonaceae)

Abstract A new styrylpyrone derivative (+)-5β-hydroxygoniothalamin (1) was isolated from the stem bark of Goniothalamus dolichocarpus. The structure and stereochemistry of (1) and its diastereoisomer (+)-5α-hydroxygoniothalamin (2) were established by NMR spectra, X-ray crystallography and partial synthesis.