Efficacy and safety of sarolaner (Simparica(®)) in the treatment and control of naturally occurring flea infestations in dogs presented as veterinary patients in Australia.

Background The efficacy and safety of a novel isoxazoline compound, sarolaner (Simparica®, Zoetis) and spinosad (Comfortis®, Elanco) as a positive control were evaluated for the treatment and control of natural flea infestations on dogs in two randomised, blinded, multi-centric clinical trials conducted in 11 veterinary clinics in northeastern and southeastern states of Australia.