Lonic Liquids-based Ultrasonic -assisted Extraction Of Total Flavonoids From Manilkara Zapota Leaves

In the present research, single-factor experiments and a three-variable, five-level central composite design were performed to study on the ionic liquids-based ultrasoni-assisted extraction of total flavonoids from Manilkara zapota leaves. The optimum parameters were: 0.95 M (C4MIM)Br, liquid/ solid ratio 33.1:1 mL·g -1 , extraction duration 30.3 min. Under the optimal conditions, the average extraction yields of total flavonoids were 12.42%.