Factor V Leiden Mutation Detected After a Circumcision in a Child: a Case Report

Factor V Leiden mutation is a rare anomaly, which is prone to increase the thrombotic incidents in those who have the abnormality compared to the normal population. Herein, we report a patient with Factor V Leiden mutation, which was detected post-operatively during evaluation of ecchymosis and ischemia on the glans penis and penile skin following skin degloving and circumcision. Luckily, glans ischemia responded hyperbaric oxygen treatment and intravenous pentoxyphylline therapy. Factor V Leiden mutation is a “Hidden Danger,” which the surgeons should keep in mind in cases of post-operative venous thrombosis leading to ecchymosis and superficial or deep tissue loss.