Tuberculomas of central nervous system: A case series and review of literature

Background: Central nervous system (CNS) tuberculosis (TB) is rare complication of systemic tuberculosis. It can lead to abscess, tuberculoma, meningitis, or other manifestations. Sometimes it is difficult to diagnosis intracranial tuberculosis as clinical and imaging features resemble various other diseases, even malignancy. Most of these cases are found in immunocompromised patients. Antituberculosis therapy is the treatment of choice which significantly reduces the mortality. Case series: Here, we are reporting a case series of CNS TB manifesting as tuberculoma in immunocompetent patients. All the patients showed clinical improvement after treatment with a combination of antituberculosis drug and corticosteroid. Conclusion: Central nervous system tuberculoma in immunocompetent patient is a rare CNS TB manifestation and its diagnosis remain a challenge since its clinical symptoms and radiological findings could mimic other diseases such as pyogenic abscess, toxoplasmosis, neurocysticercosis, sarcoidosis, malignancy etc.