Re: Simultaneous Detection of Three Phosphodiesterase Type 5 Inhibitors and Eight of Their Analogs in Lifestyle Products and Screening for Adulterants by High-Performance Thin-Layer Chromatography

available at http://www.ncbi.nlm.nih.gov/pubmed/26525240 Re: Detection of a Tadalafil Analogue as an Adulterant in a Dietary Supplement for Erectile Dysfunction J. Ulloa, L. Sambrotta, F. Redko, O. N. Mazza, G. Garrido, E. F. Becher and L. Muschietti C atedra de Farmacognosia, Facultad de Farmacia y Bioquimica (UBA), IQUIMEFA (UBA-CONICET), Buenos Aires, Argentina J Sex Med 2015; 12: 152e157. doi: 10.1111/jsm.12759 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/25402198 Re: Isolation and Characterization of a Tadalafil Analogue, N-Cyclopentyl Nortadalafil in Health Supplement Y. Xu, C. L. Kee, X. Ge, M. Y. Low and H. L. Koh Pharmaceutical Laboratory, Applied Sciences Group, Health Sciences Authority and Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore J Pharm Biomed Anal 2016; 118: 235e241. doi: 10.1016/j.jpba.2015.08.005 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/26580820 Re: Separation and Identification of a Novel Tadalafil Analogue Adulterant in a Dietary Supplement Y. C. Huang, H. C. Lee, Y. L. Lin, C. Y. Li, C. F. Tsai and H. F. Cheng Division of Research and Analysis, Taiwan Food and Drug Administration, and Division of Chinese Medicinal Chemistry, National Research Institute of Chinese Medicine, Taipei and Department of Applied Chemistry, National Pingtung University, Pingtung, Taiwan, ROC Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2016; 33: 179e185. doi: 10.1080/19440049.2015.1125531 Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/26635133 Editorial Comment: As can be readily seen in these 4 reports, a tadalafil-like compound was identified in health supplements containing a variety of substances studied in Australia, Latin America, Singapore and Taiwan. This is important information for the consumer as well as the clinician.