L-α-아미노산의 주기적 도포에 의한 피부개선 효능과 소비자 체감 효능 연구

In this study, L-α-amino acid, which is a constituent of natural moisturizing factor, was applied to skin in periodic cycle to improve skin tone and texture roughness. Based on the polarity of the alkyl group (R) of the L-α-amino acid, the acid was categorized into two groups and their efficacy was studied. As a result, it was found that the improvement rate of L-α-amino acid complex with polar alkyl group (L-α-AAC-1) is 21% higher than that of L-α-amino acid complex with non-polar alkyl group (L-α-AAC-2). For clinical trials, emulsions containing L-α-amino acid complex (L-α-AAC-1) were applied to the randomly selected 20 to 40 year old female participants, as an experimental group, on the right facial cheek once per day for 8 weeks, and emulsions without L-α-amino acid complex, as a control group, were applied to the left facial cheek in the same way. Improvements in skin tone were measured using JANUS® equipment and analyzed using image analysis software. Skin texture improvement was measured and analyzed mechanically using the phaseshift rapid in-vivo measurement of the skin (PRIMOS) equipment. As a result, improvements of skin tone and skin texture were 11.7% and 6.7%, respectively. In addition, a questionnaire survey was conducted to the participants on the aesthetic improvement and the degree of the feeling of skin improvement. The results suggest that L-α-amino acid can be used as a cosmetic substance that can provide aesthetic satisfaction through physiological skin tone and texture roughness.