Severe peach allergy in patients non-sensitized to Pru p 3

Background Allergy to Rosaceae is the fourth leading cause of food allergy in children in France. Typically, in Northern Europe, there is a prior sensitization to birch, through a PR-10 protein, while in Southern Europe the allergy is often preceded by a sensitization to a Lipid Transfer Protein (LTP). In Spain it is often recorded as a subsequent sensitization to apple (cross-reaction between Pru p 3 and Mal d 3). Beside, it has to be pointed out the frequent association between allergy to cypress and peach.