Polysomnographic abnormalities in patients with vascular cognitive impairment-no dementia

Abstract Objectives We aimed to investigate subjective sleep quality and polysomnographic sleep structure features in patients with vascular cognitive impairment-no dementia (VCIND). Methods Fifty-six patients with VCIND, 48 patients with simple stroke (without cognitive impairment), and 48 control subjects were included. The Pittsburgh Sleep Quality Index (PSQI) and polysomnography (PSG) were used to analyze their sleep characteristics. The Montreal Cognitive Assessment (MoCA) was conducted to assess mental state. Results Patients with VCIND had higher PSQI scores compared with control subjects and simple stroke patients ( P P r =0.632; P r =−0.787, −0.740, −0.772, respectively; P Conclusions VCIND patients had different abnormal sleep features, including decreased SE, increased PLMS, and prolonged SL and sleep fragmentation. Abnormal sleep in VCIND may be associated with cognitive impairment.