Comparison of in vitro activity of ciprofloxacin and pefloxacin against strains isolated from clinical material

: The susceptibility of 392 strains of pathogenic bacteria isolated from clinical material of hospitalized patients in Institute for Chest Diseases Golnik were studied. 100 strains of Escherichia coli, 56 strains of Enterobacter spp., 40 strains of Proteus mirabilis, 50 strains of Gram negative nonfermentative bacteria, 46 strains of Pseudomonas aeruginosa and 100 strains of Staphylococcus aureus were tested. Minimal inhibitory concentrations of ciprofloxacin and pefloxacin were determined by agar dilution test. The susceptibility of tested strains is greater to ciprofloxacin, except susceptibility of strains of Staphylococcus aureus, which is greater to pefloxacin. Strains of nonfermentative bacteria have lower susceptibility to both quinolones.