Scalable Purification of Viral Vectors for Gene Therapy: An Appraisal of Downstream Processing Approaches

Process concerns associated with viral-vectors gene delivery currently focus on effective purification, as described by these authors from the Centre for the Advancement of Sustainable Medical Innovation and Sartorius Stedim Biotech. For research into cell-delivered gene therapy platforms to continue toward development, process characterization and development work are still in need of refinement.