Fatal Thrombosis After Factor VII Administration During Extracorporeal Membrane Oxygenation

p D s EVERE BLEEDING IS A relatively uncommon compli tion of cardiac surgery. However, when it occurs, ssociated with increased morbidity and mortality. Recom ant activated factor VII (rFVIIa) is a procoagulant that merged as a novel therapy for intractable hemorrhage ardiac surgery in the last decade. 1,2 It has been used in diff nt situations as a rescue agent, and its successful use has escribed in several case reports and series. A case in FVIIa was used unsuccessfully to treat intractable hemorrh s reported. The presentation of its systemic effects was atic and suggests that this agent should be used with ex aution in similar situations.