Toxicity and efficacy of vitrectomy fluids: amphotericin B methyl ester in the treatment of experimental fungal endophthalmitis.

: The maximum nontoxic dose of amphotericin B methyl ester in vitrectomy infusion fluid was found to be 75 microgram/ml. Experimentally induced fungal endophthalmitis in rabbits was cured by vitrectomy using infusion fluid that contained 10 microgram/ml of amphotericin B methyl ester.