Research progress of circulating tumor DNA in ovrian cancer

With the continued development of molecular biology technologies, circulating tumor DNA (ctDNA) has shown certain value in the diagnosis and treatment of malignant tumors. The emergence of next generation sequencing technology makes ctDNA detection more accurate and rapid. ctDNA plays a certain role in the early diagnosis, disease monitoring, therapeutic evaluation and medication guide of ovarian cancer by virtue of its safety and non-invasiveness. The application of ctDNA detection is insufficient at present, but with the continuous development of sequencing technology, ctDNA will play increasingly important roles in the diagnosis, personalized treatment and prognosis evaluation of ovarian cancer. Key words: Ovarian neoplasms; Circulating tumor DNA