Paired nociceptive blink stimuli can facilitate trigeminofacial circuit at a long inter-stimulus interval

Backgrounds:Conditioned responses of paired nociceptive blink reflex (nBR) can reflect the excitability of trigeminofacial circuit. In the present study, we studied paired homotopic nBR with different inter-stimulus intervals (ISI). By monitoring different ISIs and consequential conditioned R2 of nB