Cornelia de lange syndrome with cleft palate

Abstract 4 cases of Cornelia de Lange syndrome with cleft palate are presented. All cases had the characteristic features of this syndrome. As to oral manifestations, high arches were noted in 2 cases, cleft of hard and soft palate in 1 case, submucous cleft palate in 2 cases. As the other abnormalities, partial anodontia and microdontia were presented. In this report, characteristic features of these 4 cases with referential literature are described.