Selcetive biohydroxylation of 1-substituted adamantanes using Absidia cylindrospora(I.M.I. 342950)

The biohydroxylation of 1-substituted adamantanes using Absidia cylindrospora in a whole-cell oxidation system exclusively generated 3-hydroxy and 4ax-hydroxy derivatives; the assignments were confirmed by three X-ray crystal structure determinations.